2010


Cui J, Saevarsdottir S, Thomson B, Padyukov L, van der Helm-van Mil AH, Nititham J, Hughes LB, de Vries N, Raychaudhuri S, Alfredsson L, Askling J, Wedrén S, Ding B, Guiducci C, Wolbink GJ, Crusius JB, van der Horst-Bruinsma IE, Herenius M, Weinblatt ME, Shadick NA, Worthington J, Batliwalla F, Kern M, Morgan AW, Wilson AG, Isaacs JD, Hyrich K, BRAGGSS, Seldin MF, Moreland LW, Behrens TW, Allaart CF, Criswell LA, Huizinga TW, Tak PP, Bridges SL Jr, Toes RE, Barton A, Klareskog L, Peter K. Gregersen PK, Karlson EW, Plenge RM. PTPRC rheumatoid arthritis risk allele is also associated with response to anti-TNF therapy. Arthritis Rheum 2010; Mar 22 [Epub ahead of print] Abstract

Simard JF, Stoll ML, Shadick NA, Karlson EW, Solomon DH. Validity of self-report of infections in a longitudinal cohort of patients with rheumatoid arthritis differs by source of report and infection severity. J Clin Epidemiol. 2010, April 27[Epub ahead of print] Abstract

Ercan A, Cui J, Chatterton DE, Deane KD, Hazen MM, Brintnell W, O’Donnell CI, Derber LA, Weinblatt ME, Shadick NA, Bell DA,Cairns E, Solomon DH, Holers VM, Rudd PM, Lee DM IgG Galactosylation aberrancy precedes disease onset, correlates with disease activity and is prevalent in autoantibodies in rheumatoid arthritis. Arthritis Rheum 2010; April 29. Abstract

Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, Li Y, Kurreeman FAS, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos CI, Ardlie KG, BIRAC Consortium, Barton A, Bowes J, Brower E, Burtt N, Cantanese JJ, Coblyn J, Coenen MJH, Costenbader KH, Criswell LA, Crusius JBA, Cui J, de Bakker PIW, De Jager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TWJ, Kastner DL, Ke X, Lee AT, Liu X, Martin P, Morgan AW, Padyuknov L, Posthumus MD, Radstake TRDJ, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, van der Helm-van Mil AHM, van der Horst-Bruinsma IE, van der Schoot CE, van Riel PLCM, Weinblatt, ME, Wilson AG, Wolbink GJ, Wordsworth P, YEAR Consortium, Wijmenga C, Karlson EW, Toes REM, de Vries N, Begovich AB, Worthington J, Siminovitch KA, Gregersen PK, Klareskog L, Plenge RM. Genome Wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 2010 Nat Genet; Jun;42(6):508-14. Epub 2010 May 9 Abstract

Tan W, Wu H, Zhao J, Derber LA, Lee DM, Shadick NA, Conn DL, Smith EA, Gersuk VH, Nepom GT, Moreland LW, Furst DE, Thompson SD, Jonas BL, Michael Holers V, Glass DN, Chen PP, Bridges SL Jr, Weinblatt ME, Paulus HE, Tsao BP. A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis. Arthritis Rheum. 2010 Jun 7. [Epub ahead of print] Abstract



2009


Sonali P. Desai, Ellen M. Gravallese, Nancy A. Shadick, Roberta Glass, Jing Cui, Michelle Frits, Lori B. Chibnik, Nancy Maher, Michael E. Weinblatt, Daniel H. Solomon. Hand Bone Mineral Density is Associated with Both Total Hip and Lumbar Spine Bone Mineral Density in Postmenopausal Women with RA. Rheumatology (Oxford) 2010;49:513-9. Abstract

Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, Catanese JJ, Xie G, Stahl EA, Chen R, Alfredsson L, Amos CI, Ardlie KG; BIRAC Consortium, Barton A, Bowes J, Burtt NP, Chang M, Coblyn J, Costenbader KH, Criswell LA, Crusius JB, Cui J, De Jager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TW, Kastner DL, Ke X, Kurreeman FA, Lee AT, Liu X, Li Y, Martin P, Morgan AW, Padyukov L, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, van der Helm-van Mil AH, van der Horst-Bruinsma IE, Weinblatt ME, Wilson AG, Wolbink GJ, Wordsworth P; YEAR Consortium, Altshuler D, Karlson EW, Toes RE, de Vries N, Begovich AB, Siminovitch KA, Worthington J, Klareskog L, Gregersen PK, Daly MJ, Plenge RM. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet. 2009 Dec;41(12):1313-8. Abstract

Solomon DH, Finkelstein JS, Shadick NA, LeBoff MS, Winalski CS, Stedman M, Glass R, Brookhart MA, Weinblatt MW, Gravallese EM. The Relationship Between Focal Erosions and Generalized Osteoporosis in Postmenopausal Women With Rheumatoid Arthritis. Arthritis & Rheumatism. 2009 Abstract

Lee YC, Cui J, Costenbader KH, Shadick NA, Weinblatt ME, Karlson, EW. Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate. Rheumatology (Oxford). 2009 Abstract

Stoll ML, Solomon DH, Batra KL, Simard JF, Karlson EW, Dellaripa PF, Weinblatt ME, Glass R, Shadick NA. TNF alpha inhibitors may improve asthma symptoms: a case study of 12 patients with rheumatoid arthritis and asthma. Journal of Clinical Rheumatology (In press) 2009.

Cui J, Taylor KE, DeStefano AL, Criswell LA, Izmailova E, Parker A, Roubenoff R, Plenge RM, Wienblatt ME, Shadick NA, Karlson EW. Genome Wide Association Study of Determinants of Anti-cyclic Citrullinated Peptide. Molecular Medicine. 2009; (In Press).



2008


Soumya Raychaudhuri1, Elaine F Remmers, Annette T Lee, Rachel Hackett1, Candace Guiducci1, Noel P Burtt1, Lauren Gianniny1, Benjamin D Korman, Leonid Padyukov, Fina A S Kurreeman, Monica Chang, Joseph J Catanese, Bo Ding, Sandra Wong1, Annette H M van der Helm-van Mil, Benjamin M Neale, Jonathan Coblyn, Jing Cui, Paul P Tak, Gert Jan Wolbink, J Bart A Crusius, Irene E van der Horst-Bruinsma, Lindsey A Criswell, Christopher I Amos, Michael F Seldin, Daniel L Kastner, Kristin G Ardlie, Lars Alfredsson, Karen H Costenbader, David Altshuler, Tom W J Huizinga, Nancy A Shadick, Michael E Weinblatt, Niek de Vries, Jane Worthington, Mark Seielstad, Rene E M Toes, Elizabeth W Karlson, Ann B Begovich, Lars Klareskog, Peter K Gregersen, Mark J Daly & Robert M Plenge “Common variants at CD40 and other loci confer risk of rheumatoid arthritis,”Nature Genetics (in press)

Stoll ML, Solomon DH, Batra KL, Simard JF, Karlson EW, Dellaripa PF,Weinblatt ME, Glass R, Shadick NA. TNF Inhibitors May Improve Asthma Symptoms: A Case Series of 12 Patients with Rheumatoid Arthritis andAsthma. J Clin Rheumatol, manuscript in press.

Johnsen AK, Plenge RM, Butty V, Campbell C, Dieguez-Gonzalez R, Gomez-Reino JJ, Shadick N, Weinblatt M, Gonzalez A, Gregersen PK, Benoist C, Mathis D. A broad analysis of IL1 polymorphism and rheumatoid arthritis.Arthritis Rheum. 2008 Jul;58(7):1947-57. Abstract

Agarwal SK, Glass RJ, Shadick NA, Coblyn JS, Anderson RJ, Maher NE, Weinblatt ME, Solomon DH. Predictors of discontinuation of tumor necrosis factor inhibitors in patients with rheumatoid arthritis. J Rheumatol. 2008 Sep;35(9):1737-44. Abstract

Roubenoff R, Beckman E, Weinblatt, MW, Shadick NA, Gregersen PK. Biological significance of anti-cyclic citrullinated peptide antibody in rheumatoid arthritis. Ann Intern Med 2008; 148 (5):403; author reply 403-4. . Comment

Royle L, Campbell MP, Radcliffe CM, White DM, Harvey DJ, Abrahams JL, Kim YG, Henry GW, Shadick NA, Weinblatt ME, Lee DM, Rudd PM, Dwek RA. HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software.. Anal Biochem 2008; 376 (1):1-12. . Abstract



2007


Plenge RM, Cotsapas C, Davies L, Price AL, de Bakker PI, Maller J, Pe’er I, Burtt NP, Blumenstiel B, DeFelice M, Parkin M, Barry R, Winslow W, Healy C, Graham RR, Neale BM, Izmailova E, Roubenoff R, Parker AN, Glass R, Karlson EW, Maher N, Hafler DA, Lee DM, Seldin MF, Remmers EF, Lee AT, Padyukov L, Alfredsson L, Coblyn J, Weinblatt ME, Gabriel SB, Purcell S, Klareskog L, Gregersen PK, Shadick NA, Daly MJ, Altshuler D.Two independent alleles at 6q23 associated with risk of rheumatoid arthritis, Nature Genetics, 2007 Oct; [Epub ahead of print] Abstract

Parker A, Izmailova ES, Narang J, Badola S, Le T, Roubenoff R, Ginsburg GS, Maier A, Coblyn JS, Shadick NA, Weinblatt ME Peripheral Blood Expression of Nuclear Factor-?B-Regulated Genes Is Associated with Rheumatoid Arthritis Disease Activity and Responds Differentially to Anti-Tumor Necrosis Factor-? versus Methotrexate, , J Rheumatol 2007 Sep;34(9):1817-22. Epub 2007 Aug 1. Abstract

Karlson EW, Chibnik LB, Cui J, Plenge RM, Glass RJ, Maher NE, Parker A, Roubenoff R, Izmailova E, Coblyn JS, Weinblatt ME, Shadick NA. Associations between HLA, PTPN22, CTLA4 genotypes and RA phenotypes of autoantibody status, age at diagnosis, and erosions in a large cohort study. Ann Rheum Dis. 2007 Jul 31; [Epub ahead of print]? Abstract
Heller JE, Shadick NA. Outcomes in rheumatoid arthritis: incorporating the patient perspective.Curr Opin Rheumatol. 2007 Mar;19(2):101-5. Review. Abstract

Shadick NA, Heller JE, Weinblatt ME, Maher NE, Cui J, Ginsburg GS, Coblyn J, Anderson R, Solomon DH, Roubenoff R, Parker A. Opposing effects of the D70 mutation and the shared epitope in HLA-DR4 on disease activity and certain disease phenotypes in rheumatoid arthritis.Ann Rheum Dis. 2007 May 21; [Epub ahead of print] Abstract

Solomon DH, Stedman M, Licari A, Weinblatt ME, Maher N, Shadick N. Agreement between patient report and medical record review for medications used for rheumatoid arthritis: the accuracy of self-reported medication information in patient registries.Arthritis Rheum. 2007 Mar 15;57(2):234-9. Abstract



2006


Benito-Garcia E, Heller JE, Chibnik LB, Maher NE, Matthews HM, Bilics JA, Weinblatt ME, Shadick NA .Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis. J Rheumatol. 2006 Jul;33(7):1275-81. Abstract

Costenbader KH, Glass R, Cui J, Shadick N. Risk of serious infections and malignancies with anti-TNF antibody therapy in rheumatoid arthritis. JAMA. 2006 Nov 8;296(18):2201; author reply 2203-4. No abstract available. Excerpt

Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006 Aug;38(8):904-9. Epub 2006 Jul 23. Abstract

Shadick NA, Cook NR, Karlson EW, Ridker PM, Maher NE, Manson JE, Buring JE, Lee IM. C-reactive protein in the prediction of rheumatoid arthritis in women. Arch Intern Med. 2006 Dec 11-25;166(22):2490-4. Abstract

Sato M, Schneeweiss S, Scranton R, Katz JN, Weinblatt ME, Avorn J, Ting G, Shadick NA, Solomon DH. The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28. Arthritis Res Ther. 2006;8(3):R57. Epub 2006 Mar 14. Abstract